Ontology highlight
ABSTRACT:
ORGANISM(S): Cellular Organisms Synechocystis
SUBMITTER: Tomohisa Hasunuma
PROVIDER: PXD071907 | JPOST Repository | Wed May 06 00:00:00 GMT+01:00 2026
REPOSITORIES: jPOST
| Action | DRS | |||
|---|---|---|---|---|
| 2024102103_TMT1.pdResult | Other | |||
| 2024102103_TMT2.pdResult | Other | |||
| 2024102103_TMT3.pdResult | Other | |||
| 2024102103_TMT4.pdResult | Other | |||
| 2024102103_TMT5.pdResult | Other |
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Proceedings of the National Academy of Sciences of the United States of America 20260519 21
Disulfide bonds act as reversible switches that regulate cellular function in nearly all organisms. Their behavior is set by the midpoint potential (<i>E</i><sub>m</sub>), yet <i>E</i><sub>m</sub> is known for only a small number of sites, mostly in purified proteins studied away from their natural partners. We developed a mass-spectrometry workflow that measures <i>E</i><sub>m</sub> directly from native cell lysates. By equilibrating proteins of the cyanobacterium <i>Synechocystis</i> sp. PCC 6 ...[more]