Proteomics

Dataset Information

48

CDK7/TFIIH regulates SETD1A/B activity


ABSTRACT: Affinity Purification and Mass Spectrometry (AP-MS) using the phosphorylated RNAPII C-terminal domain (CTD) identified the capping enzyme and the H3K4 methyltransferase complex SETD1A/B. Subsequent inhibition of CDK7 revealed displaced H3K4me3 marks at the 3'-end of genes.

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Homo sapiens  

SUBMITTER: Dylan J Taatjes   William M. Old  

PROVIDER: MSV000081069 | MassIVE | Wed May 10 07:39:00 BST 2017

SECONDARY ACCESSION(S): PXD006485

REPOSITORIES: MassIVE

Dataset's files

Source:
Action DRS
Other
params.xml Xml
methods.docx Other
MS supplemental.xlsx Xlsx
CCE_CTD0_1Dsinglepump_120m_20130123_orb1.raw Raw
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