Proteomics

Dataset Information

40

Omega-6 and omega-3 oxylipins are implicated in soybean oil-induced obesity in mice


ABSTRACT: Soybean oil consumption is increasing worldwide and parallels the rise in obesity. Rich in unsaturated fats, especially linoleic acid, soybean oil is assumed to be healthy, and yet it induces obesity, diabetes, insulin resistance and fatty liver in mice. Here, we show that the genetically modified soybean oil Plenish, which came on the U.S. market in 2014 and is low in linoleic acid, induces less obesity than conventional soybean oil in C57BL/6male mice.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Mus musculus  

SUBMITTER: Frances M. Sladeka  

PROVIDER: MSV000081149 | MassIVE | Thu Jun 08 09:55:00 BST 2017

SECONDARY ACCESSION(S): PXD006681

REPOSITORIES: MassIVE

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Publications


Soybean oil consumption is increasing worldwide and parallels a rise in obesity. Rich in unsaturated fats, especially linoleic acid, soybean oil is assumed to be healthy, and yet it induces obesity, diabetes, insulin resistance, and fatty liver in mice. Here, we show that the genetically modified soybean oil Plenish, which came on the U.S. market in 2014 and is low in linoleic acid, induces less obesity than conventional soybean oil in C57BL/6 male mice. Proteomic analysis of the liver reveals g  ...[more]

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