Differences in proteomic microglia from male and female brains
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Mus Musculus (ncbitaxon:10090)
SUBMITTER: 
Susanne Wolff
PROVIDER: MSV000081661 | MassIVE | Thu Nov 02 03:38:00 GMT 2017
SECONDARY ACCESSION(S): PXD008114
REPOSITORIES: MassIVE
Publications
Transcriptional and Translational Differences of Microglia from Male and Female Brains.
Guneykaya Dilansu D Ivanov Andranik A Hernandez Daniel Perez DP Haage Verena V Wojtas Bartosz B Meyer Niklas N Maricos Meron M Jordan Philipp P Buonfiglioli Alice A Gielniewski Bartlomiej B Ochocka Natalia N Cömert Cagla C Friedrich Corinna C Artiles Lorena Suarez LS Kaminska Bozena B Mertins Philipp P Beule Dieter D Kettenmann Helmut H Wolf Susanne A SA
Cell reports 20180901 10
Sex differences in brain structure and function are of substantial scientific interest because of sex-related susceptibility to psychiatric and neurological disorders. Neuroinflammation is a common denominator of many of these diseases, and thus microglia, as the brain's immunocompetent cells, have come into focus in sex-specific studies. Here, we show differences in the structure, function, and transcriptomic and proteomic profiles in microglia freshly isolated from male and female mouse brains ...[more]
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