Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap XL
ORGANISM(S): Xenopus Laevis (ncbitaxon:8355)
SUBMITTER: Hollis T. Cline
PROVIDER: MSV000081914 | MassIVE | Thu Jan 11 14:15:00 GMT 2018
SECONDARY ACCESSION(S): PXD008659
REPOSITORIES: MassIVE
Shen Wanhua W Liu Han-Hsuan HH Schiapparelli Lucio L McClatchy Daniel D He Hai-Yan HY Yates John R JR Cline Hollis T HT
Cell reports 20140213 4
Neural plasticity requires protein synthesis, but the identity of newly synthesized proteins generated in response to plasticity-inducing stimuli remains unclear. We used in vivo bio-orthogonal noncanonical amino acid tagging (BONCAT) with the methionine analog azidohomoalanine (AHA) combined with the multidimensional protein identification technique (MudPIT) to identify proteins that are synthesized in the tadpole brain over 24 hr. We induced conditioning-dependent plasticity of visual avoidanc ...[more]