Proteomics

Dataset Information

0

Data for: A practical guide for analysis of histone post-translational modifications by mass spectrometry: best practices and pitfalls

ABSTRACT: Histone proteomics from 5 human cell lines, discussed in publication: "A practical guide for analysis of histone post-translational modifications by mass spectrometry: best practices and pitfalls". Further explanation of data types, methods, and analysis are available in Data Explanation document in the Methods and Protocols folder.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: John Denu  

PROVIDER: MSV000084298 | MassIVE |

REPOSITORIES: MassIVE

Json Xml

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1
altmetric image

Publications

A practical guide for analysis of histone post-translational modifications by mass spectrometry: Best practices and pitfalls.

Thomas Sydney P SP   Haws Spencer A SA   Borth Laura E LE   Denu John M JM  

Methods (San Diego, Calif.) 20191207

Advances in mass spectrometry (MS) have revolutionized the ability to measure global changes in histone post-translational modifications (PTMs). The method routinely quantifies over 60 modification states in a single sample, far exceeding the capabilities of traditional western blotting. Thus, MS-based histone analysis has become an increasingly popular tool for understanding how genetic and environmental factors influence epigenetic states. However, histone proteomics experiments exhibit unique  ...[more]

Similar Datasets

Genomics RNA silencing by CRISPR in plants does not require Cas13
2021-12-07 | GSE171980 | GEO
Transcriptomics Transcriptome profiling of maize transcription factor mutants to probe gene regulatory network predictions
2024-10-23 | GSE280139 | GEO
Genomics
| PRJNA628141 | ENA
Genomics Small RNA sequencing based identification of miRNAs in Cnaphalocrocis medinalis
2024-07-04 | GSE271187 | GEO
Proteomics Short-Term Starvation Activates AMPK and Restores Mitochondrial Inorganic Polyphosphate, but Fails to Reverse Associated Neuronal Senescence
2024-07-10 | MSV000095282 | MassIVE
Genomics
| PRJNA1139678 | ENA
Transcriptomics In vitro effect of the integrine LAMA4 on motility and cluster formation of human chondrocytes
2015-12-22 | E-GEOD-68428 | biostudies-arrayexpress
Genomics Single residues in the histone core domain guide transcription
| PRJNA1174139 | ENA
Proteomics 20240726_EPAD_MICU_fecaltargetedpanels
2024-07-26 | MSV000095462 | MassIVE
Other Comparison of methods to generate a pooled Enterococcus faecalis Tn library from arrayed library plates
2023-05-22 | GSE233193 | GEO