Brevetoxin induces a shift in the redox state of the proteome and unfolded protein response in human lymphoblast cells that can be alleviated with the acrolein scavenger MESNA

ABSTRACT: Human lymphoblast cells (GM05581) were treated with (i) brevetoxin-2 (5 uM) or (ii) a combination of brevetoxin-2 (5 uM) and sodium 2-mercaptoethyl sulfonic acid (500 uM) or (iii) equal volume of vehicle (DMSO, control) for 24 h. Each sample is an iodoTMT6plex with 2 replicates of each of the above conditions.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Kathleen Rein  

PROVIDER: MSV000090293 | MassIVE |

REPOSITORIES: MassIVE