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Alterations in the secretome composition arising from YIPF5 depletion or mutation

ABSTRACT: Secretome analysis was conducted on MCF10A cells with various conditions, including wild-type (wt) cells, YIPF5-depleted cells, cells with mutated YIPF5, and cells with re-expression of wild-type YIPF5. The primary objective was to discern alterations in the secretome composition arising from YIPF5 depletion or mutation. This investigation aimed to shed light on the influence of YIPF5 on the secretory profile of MCF10A cells, providing insights into potential changes in extracellular signaling and cellular communication associated with YIPF5 status.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Christoph Kaether

PROVIDER: MSV000093769 | MassIVE | Thu Jan 04 13:47:00 GMT 2024

SECONDARY ACCESSION(S): PXD048259

REPOSITORIES: MassIVE

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