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Proteomics analaysis of mouse KP tumors with normal and western diet

ABSTRACT: The dataset comprises KP lung tumors derived from mice fed either a normal or Western diet, analyzed to identify changes in signaling pathways influenced by dietary differences. Protein samples underwent TMT-based labeling, fractionation, and mass spectrometry, including Orbitrap MS3 for proteome and phosphorylated peptide analyses, ensuring high-resolution data collection. Phosphorylation site localization and protein quantification were rigorously filtered with a 1% FDR threshold and corrected for isotopic impurities. These analyses aim to uncover how dietary variations modulate key signaling mechanisms in lung tumor progression.

INSTRUMENT(S): Orbitrap Eclipse

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

SUBMITTER: ramon sun

PROVIDER: MSV000096917 | MassIVE | Wed Jan 22 17:14:00 GMT 2025

SECONDARY ACCESSION(S): PXD060090

REPOSITORIES: MassIVE

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