Spectral quality guided optimization of hybrid EAciD fragmentation on the ZenoTOF 7600 system

ABSTRACT: Systematically optimized N-glycoproteomics method combining EAD and CID on the ZenoTOF 7600. Several dynamic CID parameters were optimized, next EAD was added using different kinetic energy values. Optimization was performed on glycopeptide enriched human plasma. After optimization, the method was tested on a small cohort of cancer patient sera.

INSTRUMENT(S): ZenoTOF 7600

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: A.J.R. Heck  

PROVIDER: MSV000098519 | MassIVE | Tue Jul 15 02:54:00 BST 2025

REPOSITORIES: MassIVE