Dataset Information
Metabolic Reprogramming in Tumor-Associated Macrophages during Murine Hepatocellular Carcinoma Progression
Ontology highlight
ABSTRACT: To investigate the impact of Wdr4 on the metabolic reprogramming of tumor-associated macrophages (TAMs) in hepatocellular carcinoma (HCC), we established an orthotopic HCC model in Wdr4-f/f and Wdr4 conditional knockout (Wdr4-cKO) mice. TAMs were subsequently isolated via flow cytometry-based cell sorting. Untargeted metabolomics analysis was performed to identify metabolic alterations in TAMs associated with Wdr4 deficiency.
INSTRUMENT(S): Liquid Chromatography MS - positive, Liquid Chromatography MS - negative
PROVIDER: MTBLS12764 | MetaboLights | 2025-09-28
REPOSITORIES: MetaboLights
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| KO-1.wiff | Wiff | |||
| KO-1.wiff.scan | Wiff | |||
| KO-2.wiff | Wiff | |||
| KO-2.wiff.scan | Wiff | |||
| KO-3.wiff | Wiff |
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