Changes in the Metabolome of Alexandrium pacificum upon Addition of Algicidal Microorganisms

ABSTRACT: Furthermore, transcriptomic analysis revealed that algal metabolic pathway genes were differentially expressed under treatment with the fungus–bacterium composite system. Genes involved in glycolysis and the pentose phosphate pathway were upregulated, enhancing energy supply, antioxidant capacity, and biosynthetic repair, respectively. Genes related to the TCA cycle and fatty acid degradation were upregulated, improving respiratory energy supply, supporting anabolism, initiating emergency energy provision, and participating in cellular repair. Photosynthetic system genes were downregulated, reducing photosynthetic efficiency and shifting metabolic priority toward stress resistance. Oxidative phosphorylation genes were upregulated to coordinate energy supply. Ribosomal genes were upregulated to activate protein translation, meeting the demands of metabolic repair and stress resistance and helping algae adapt to stressful environments.

INSTRUMENT(S): Liquid Chromatography MS - negative - reverse-phase, Liquid Chromatography MS - positive - reverse-phase

PROVIDER: MTBLS14746 | MetaboLights | 2026-06-11

REPOSITORIES: MetaboLights