Ontology highlight
ABSTRACT:
INSTRUMENT(S): Liquid Chromatography MS - negative - reverse phase
SUBMITTER: Elite Possik
PROVIDER: MTBLS3485 | MetaboLights | 2021-09-28
REPOSITORIES: MetaboLights
Possik Elite E Schmitt Clémence C Al-Mass Anfal A Bai Ying Y Côté Laurence L Morin Johanne J Erb Heidi H Oppong Abel A Kahloan Wahab W Parker J Alex JA Madiraju S R Murthy SRM Prentki Marc M
Nature communications 20220111 1
Metabolic stress due to nutrient excess and lipid accumulation is at the root of many age-associated disorders and the identification of therapeutic targets that mimic the beneficial effects of calorie restriction has clinical importance. Here, using C. elegans as a model organism, we study the roles of a recently discovered enzyme at the heart of metabolism in mammalian cells, glycerol-3-phosphate phosphatase (G3PP) (gene name Pgp) that hydrolyzes glucose-derived glycerol-3-phosphate to glycero ...[more]