Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

13C mass isotopomer analysis (LCMS flux studies) MLL-AF9 (part III)

ABSTRACT:

ORGANISM(S): Mus Musculus

TISSUE(S): Cells

PROVIDER: ST000170 | MetabolomicsWorkbench |

REPOSITORIES: MetabolomicsWorkbench

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	mwtab	Other

Items per page:

1 - 1 of 1

Similar Datasets

13C mass isotopomer analysis (LCMS flux studies) MLL-AF9 (part II)

Project description: Not available

| ST000157 | MetabolomicsWorkbench

13C mass isotopomer analysis (LCMS flux studies) MLL-AF9 (part I)

Project description: Not available

| ST000308 | MetabolomicsWorkbench

Systematic analysis of protein turnover in primary cells - Part III

Project description:To better understand proteostasis in health and disease, determination of protein half-lives is essential. We improved the precision and accuracy of peptide-ion intensity based quantification in order to enable accurate determination of protein turnover in non-dividing cells using dynamic-SILAC. This enabled precise and accurate protein half-life determination ranging from 10 to more than 1000 hours. We achieve good proteomic coverage ranging from four to six thousand proteins in several types of non-dividing cells, corresponding to a total of 9699 unique proteins over the entire dataset. Good agreement was observed in half-lives between B-cells, natural killer cells and monocytes, while hepatocytes and mouse embryonic neurons showed substantial differences. Our comprehensive dataset enabled extension and statistical validation of the previous observation that subunits of protein complexes tend to have coherent turnover. Furthermore, we observed complex architecture dependent turnover within complexes of the proteasome and the nuclear pore complex. Our method is broadly applicable and might be used to investigate protein turnover in various cell types.

2018-06-08 | PXD008513 | Pride

Integrated, Step-Wise, Mass-Isotopomeric Flux Analysis of the TCA Cycle.

Project description: Not available

| S-EPMC4635072 | biostudies-literature

Publishing 13C metabolic flux analysis studies: a review and future perspectives.

Project description: Not available

| S-EPMC5866723 | biostudies-literature

Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder.

Project description: Not available

| S-EPMC1180589 | biostudies-literature

PTM and HDX-MS analysis of DJ-1

Project description:1. PTM analysis results of DJ-1 1D-gel bands under non-reducing and reducing condition 2. HDX-MS analysis of DJ-1

2023-03-10 | PXD020690 | Pride

Radiology of fibrosis part III: genitourinary system.

Project description: Not available

| S-EPMC11223291 | biostudies-literature

Methylation studies in mole rats. Part 2

Project description:An Infinium microarray platform (GPL28271, HorvathMammalMethylChip40) was used to generate DNA methylation data from many tissues of 3 species of mole rats: Cape mole rat (Georychus capensis), Damaraland mole rat (Cryptomys damarensis), Naked mole rat (Heterocephalus glaber). We generated DNA methylation data from n=94 tissues from 3 species: Cryptomys damarensis (n=10), Georychus capensis (n=6), Heterocephalus glaber (n=78). All tissues ewere obtained from frozen tissue collection that were euthanized for other studies. Kidney (n=6), liver (n=61), skin (n=27). The tissues used in this study were obtained from post-mortem specimens from animals free from disease in compliance. Sample collection was from post-mortem material. Tissue samples were snap frozen in liquid nitrogen following dissection and transferred for storage at -80ºC. Genomic DNA was extracted using Qiagen DNeasy Blood and Tissue kit and quantified using Nanodrop and Qubit.als

2021-10-18 | GSE174778 | GEO

Flux-p: automating metabolic flux analysis.

Project description: Not available

| S-EPMC3901227 | biostudies-literature