Browse
Submit Data
Databases
API
Help

Dataset Information

119 Views

1 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 1037

NMR based quantitative metabolomics studies of heart and lung from mouse exposed to whole body high dose gamma and proton radiation (part II)

ABSTRACT: Tissue extracts from ionizing readiation exposed mouse lung and controls were compared via NMR based metabolomic analysis

INSTRUMENT(S): FT-NMR

ORGANISM(S): Mouse Mus Musculus

TISSUE(S): Lung

DISEASE(S): Radiation Exposure

SUBMITTER: Jianzhi Hu

PROVIDER: ST000480 | MetabolomicsWorkbench | Mon Aug 15 00:00:00 BST 2016

REPOSITORIES: MetabolomicsWorkbench

ACCESS DATA

Json Xml

Similar Datasets

NMR based quantitative metabolomics studies of heart and lung from mouse exposed to whole body high dose gamma and proton radiation (part I)

Project description:Tissue extracts from ionizing readiation exposed mouse heart and controls were compared via NMR based metabolomic analysis

2016-08-15 | ST000479 | MetabolomicsWorkbench

Transcriptional response in the heart after low-dose gamma

Project description:We report whole transcriptome sequencing of the intraventricular septum of mouse heart 2 and 6 weeks after 25 Gy ionizing radiation. The objective of this experiment was to identify genes and pathways differentially regulated by ionizing radiation in the heart. Image-guided isocentric gamma irradiation was delivered to experimental groups under isoflurane anesthesia in a single, 25 Gy dose over approximately 15 minutes. Control group animals were experimental group littermates which received anesthesia and CT imaging but no radiation. RNA was isolated from intraventricular septum using TRIzol.

2021-08-16 | GSE153981 | GEO

Metabolomics Analysis of Kidney from C57BL/6 Mouse Exposed to Ionizing Radiation

Project description:Tissue extracts from ionizing readiation exposed mouse kidney and controls were compared via NMR based metabolomic analysis

2016-10-31 | ST000500 | MetabolomicsWorkbench

NMR based Metabolomics Analysis of Liver from C57BL/6 Mouse Exposed to Ionizing Radiation

Project description:Tissue extracts from ionizing readiation exposed mouse liver and controls were compared via NMR based metabolomic analysis

2016-08-11 | ST000478 | MetabolomicsWorkbench

NMR based Metabolomics Analysis of Mouse Exposed to Gamma Radiation

Project description:Biofluid extracts from gamma readiation exposed mouse plasma and controls were compared via NMR based metabolomic analysis

2016-11-02 | ST000501 | MetabolomicsWorkbench

Quiescent keratinocytes and fibroblasts: radiation dose response

Project description:Skin is usually exposed during human exposures to ionizing radiation, however there are few experiments that evaluate the radiation responsiveness of the cells of the epidermis (keratinocytes) and those of the dermis (fibroblasts) in the same studies. We evaluated the transcriptional responses of quiesent primary keratinocytes and fibroblasts from the same individual and compared them with quiescent keratinocytes and fibroblasts that were immortalized by human telomerase (hTert). The primary transcriptional responses to 10-500 cGy ionizing radiation were p53-mediated responses; however, we did identify distinct responses between the keratinocytes and the fibroblasts. Keywords: keratinocytes and fibroblasts - dose response to ionizing radiation

2009-05-31 | GSE14466 | GEO

Inflammatory profile dysregulation in nuclear workers occupationally exposed to low-dose gamma radiation.

Project description: Not available

| S-EPMC7268544 | biostudies-literature

Metabolomic Studies of Tissue Injury in Nonhuman Primates Exposed to Gamma-Radiation.

Project description: Not available

| S-EPMC6651211 | biostudies-literature

Transgenerational DNA methylation changes in Daphnia magna exposed to chronic gamma radiation

Project description:DNA methylation epigenetic changes were analysed in Daphnia magna exposed for 25-day to chronic gamma irradiation compared to unexposed controls. Generation F0 were exposed to 6.5 μGy/h or 41.3 mG/h and let recoverd until the F3 generation without exposures to ionizing radiations. DNA-methylation patterns were analysed by WGBS on the whole organismes at the generation F0, F2 and F3 in order to detect possible transmission of DNA methylation changes to the progeny.

2018-03-01 | GSE108426 | GEO

Consequences of lethal-whole-body gamma radiation and possible ameliorative role of melatonin.

Project description: Not available

| S-EPMC4238234 | biostudies-other