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Characterization of Mycobacterium bovis MB3 genome sequence

ABSTRACT: Characterization of Mycobacterium bovis MB3 genome sequence

PROVIDER: PRJEB7272 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	CDHH01.dat.gz	Other
	CDHH01.fasta.gz	Fasta.gz
	CDHH01.master.dat	Other
	CDHH01.dat.gz	Other

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Project description:Mycobacterium bovis (M. bovis) and Mycobacterium avium subspecies paratuberculosis (MAP) are important pathogens of cattle, causing bovine tuberculosis and Johne’s disease respectively. M. bovis and MAP infect residential macrophages in the lung and intestines respectively and subvert the macrophage biology to create a survival niche. To investigate this interaction we simultaneously studied the transcriptional response of bovine monocyte-derived macrophages to infection with two strains of M. bovis (AF2122/97 and G18) and two strains of MAP (C & L1).

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