Dataset Information


Sus scrofa

ABSTRACT: Time-course analysis of intestinal postnatal response to IUGR at 0-2 and 5 days

ORGANISM(S): Sus scrofa  



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Intrauterine growth restriction modifies the developmental pattern of intestinal structure, transcriptomic profile, and bacterial colonization in neonatal pigs.

D'Inca Romain R   Kloareg Maela M   Gras-Le Guen Christèle C   Le Huërou-Luron Isabelle I  

The Journal of nutrition 20100324 5

Neonates with intrauterine growth restriction (IUGR) are prone to suffer from digestive diseases. Using neonatal pigs with IUGR, we tested the hypothesis that IUGR may induce alterations in the developmental pattern of intestinal barrier and thereby may be responsible for IUGR-associated increased morbidity. Piglets with a birth weight near the mean birth weight (+/-0.5 SD) were identified as normal birth weight (control) and piglets with a mean -2 SD lower birth weight (-30%) were defined as pi  ...[more]

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