Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: Building Prognostic Models for Breast Cancer Patients Using Clinical Variables and Gene Expression Signatures

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA117131 | ENA |

REPOSITORIES: ENA

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Publications

Building prognostic models for breast cancer patients using clinical variables and hundreds of gene expression signatures.

Fan Cheng C   Prat Aleix A   Parker Joel S JS   Liu Yufeng Y   Carey Lisa A LA   Troester Melissa A MA   Perou Charles M CM  

BMC medical genomics 20110109


Multiple breast cancer gene expression profiles have been developed that appear to provide similar abilities to predict outcome and may outperform clinical-pathologic criteria; however, the extent to which seemingly disparate profiles provide additive prognostic information is not known, nor do we know whether prognostic profiles perform equally across clinically defined breast cancer subtypes. We evaluated whether combining the prognostic powers of standard breast cancer clinical variables with  ...[more]

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