Genomics

Dataset Information

0

Rattus norvegicus


ABSTRACT: Gene expression-based assessment of the effect of PQQ

ORGANISM(S): Rattus norvegicus  

PROVIDER: PRJNA120033 | ENA |

REPOSITORIES: ENA

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Publications

Identification of transcriptional networks responding to pyrroloquinoline quinone dietary supplementation and their influence on thioredoxin expression, and the JAK/STAT and MAPK pathways.

Tchaparian Eskouhie E   Marshal Lisa L   Cutler Gene G   Bauerly Kathryn K   Chowanadisai Winyoo W   Satre Michael M   Harris Calliandra C   Rucker Robert B RB  

The Biochemical journal 20100801 3


PQQ (pyrroloquinoline quinone) improves energy utilization and reproductive performance when added to rodent diets devoid of PQQ. In the present paper we describe changes in gene expression patterns and transcriptional networks that respond to dietary PQQ restriction or pharmacological administration. Rats were fed diets either deficient in PQQ (PQQ-) or supplemented with PQQ (approx. 6 nmol of PQQ/g of food; PQQ+). In addition, groups of rats were either repleted by administering PQQ to PQQ- ra  ...[more]

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