Genomics

Dataset Information

118

Cryptococcus neoformans var. grubii H99


ABSTRACT: Effect of Nrg1 on pathogenesis of Cryptococcus neoformans

ORGANISM(S): Cryptococcus neoformans var. grubii H99  

PROVIDER: PRJNA120071 | ENA |

REPOSITORIES: ENA

altmetric image

Publications

Transcription factor Nrg1 mediates capsule formation, stress response, and pathogenesis in Cryptococcus neoformans.

Cramer Kari L KL   Gerrald Quincy D QD   Nichols Connie B CB   Price Michael S MS   Alspaugh J Andrew JA  

Eukaryotic cell 20060701 7


The Cryptococcus neoformans NRG1 gene was identified using gene microarrays to define putative transcription factor genes regulated by the cyclic AMP (cAMP) signal transduction pathway. Disruption of NRG1 results in delayed capsule formation and mating, two phenotypes that are directly controlled by cAMP signaling. Putative targets of the Nrg1 transcription factor were identified using a second genome microarray to define differences in the transcriptomes of the wild-type and nrg1 mutant strains  ...[more]

Similar Datasets

2010-05-26 | E-GEOD-10750 | ArrayExpress
2008-03-07 | GSE10750 | GEO
2012-05-20 | BMID000000141997 | BioModels
| PRJNA285298 | ENA
| PRJNA218147 | ENA
2013-07-01 | E-MTAB-1700 | ArrayExpress
| PRJNA229752 | ENA
| PRJNA225991 | ENA
| PRJNA164705 | ENA
| PRJNA359355 | ENA