Dataset Information


Homo sapiens

ABSTRACT: DHA supplementation suppresses LDLR and OLR1 gene expression in blood cells from hypertriglyceridemic men

ORGANISM(S): Homo sapiens  



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Modulation of blood cell gene expression by DHA supplementation in hypertriglyceridemic men.

Dawson Kevin K   Zhao Ling L   Adkins Yuriko Y   Vemuri Madhuri M   Rodriguez Raymond L RL   Gregg Jeffrey P JP   Kelley Darshan S DS   Hwang Daniel H DH  

The Journal of nutritional biochemistry 20110719 6

Our previous study with docosahexaenoic acid (DHA) supplementation to hypertriglyceridemic men showed that DHA reduced several risk factors for cardiovascular disease, including the plasma concentration of inflammatory markers. To determine the effect of DHA supplementation on the global gene expression pattern, we performed Affymetrix GeneChip microarray analysis of blood cells [treated with lipopolysaccharide (LPS) or vehicle] drawn before and after the supplementation of DHA from the hypertri  ...[more]

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