Dataset Information


Daphnia magna

ABSTRACT: Differential Gene Expression in Daphnia magna Suggests Distinct Modes of Action and Bioavailability for ZnO nanoparticles and Zn ions

ORGANISM(S): Daphnia magna  



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Differential gene expression in Daphnia magna suggests distinct modes of action and bioavailability for ZnO nanoparticles and Zn ions.

Poynton Helen C HC   Lazorchak James M JM   Impellitteri Christopher A CA   Smith Mark E ME   Rogers Kim K   Patra Manomita M   Hammer Katherine A KA   Allen H Joel HJ   Vulpe Chris D CD  

Environmental science & technology 20101213 2

Zinc oxide nanoparticles (ZnO NPs) are being rapidly developed for use in consumer products, wastewater treatment, and chemotherapy providing several possible routes for ZnO NP exposure to humans and aquatic organisms. Recent studies have shown that ZnO NPs undergo rapid dissolution to Zn(2+), but the relative contribution of Zn(2+) to ZnO NP bioavailability and toxicity is not clear. We show that a fraction of the ZnO NPs in suspension dissolves, and this fraction cannot account for the toxicit  ...[more]

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