Genomics

Dataset Information

412

Homo sapiens


ABSTRACT: Genome-wide binding profiles of the B-Myb-MuvB complex in HeLa cells

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA142047 | ENA |

REPOSITORIES: ENA

altmetric image

Publications

The MuvB complex sequentially recruits B-Myb and FoxM1 to promote mitotic gene expression.

Sadasivam Subhashini S   Duan Shenghua S   DeCaprio James A JA  

Genes & development 20120301 5


Cell cycle progression is dependent on two major waves of gene expression. Early cell cycle gene expression occurs during G1/S to generate factors required for DNA replication, while late cell cycle gene expression begins during G2 to prepare for mitosis. Here we demonstrate that the MuvB complex-comprised of LIN9, LIN37, LIN52, LIN54, and RBBP4-serves an essential role in three distinct transcription complexes to regulate cell cycle gene expression. The MuvB complex, together with the Rb-like p  ...[more]

Similar Datasets

2012-01-25 | E-GEOD-27031 | ArrayExpress
2012-01-25 | E-GEOD-27030 | ArrayExpress
2010-03-25 | GSE21045 | GEO
2007-11-14 | GSE8751 | GEO
2007-11-14 | GSE9087 | GEO
| PRJNA291815 | ENA
2007-07-21 | GSE8537 | GEO
| PRJNA102609 | ENA
2008-06-16 | E-GEOD-8537 | ArrayExpress
2010-09-25 | GSE24338 | GEO