Project description:We report maps of H3K4me3 and H3ac - activiting expression histone modifications in C6 rat glioma cells. The data was obtained using whole genome high throughput technology. The sequencing was performed on HiSeq Ilumina platform. Examination of H3K4me3 histone modification and H3ac histone modification in C6 rat glioma cell line
Project description:We report maps of H3K4me3 and H3ac - activiting expression histone modifications in C6 rat glioma cells. The data was obtained using whole genome high throughput technology. The sequencing was performed on HiSeq Ilumina platform.
Project description:We report a map of H3K4me3 - an activiting expression histone modification in C6 rat glioma cells. The data was obtained using whole genome high throughput technology. The sequencing was performed on Solid 5500xl platform. Examination of H3K4me3 histone modification in C6 rat glioma cell line
Project description:We report a map of H3K4me3 - an activiting expression histone modification in C6 rat glioma cells. The data was obtained using whole genome high throughput technology. The sequencing was performed on Solid 5500xl platform.
Project description:We report a map of Stat3 binding sites in C6 rat glioma cells. The data was obtained using whole genome technology using NimbleGen microarrays. Examination of Stat3 binding sites in C6 rat glioma cell line
Project description:We have grown C6 glioma cells and rat astrocytes, as well as astrocyte cells co-cultured together with C6 glioma. We performed proteome-wide LC-MS analysis of this experimental groups. The data including LC-MS/MS raw files and exported MaxQuant report. For our co-cultivated in vitro model we used astrocytes and C6 glioma cells. Astrocytes cell lines isolated from rat brain tissue. We analyzed astrocytes in two conditions: beforeand after co-cultivation. Proteins were assessed in an untargeted label-free bottom-up proteomic experiment using IDA approach (i.e. InformationDependent Acquisition) on AB Sciex TripleTOF 6600 Q-TOF mass-spectrometer coupled with LFQ (label-free quantification) approach by MaxQuant software. Dataset covers 165 samples (11 biological rand 5 technical replicates)
Project description:We report a map of Stat3 binding sites in C6 rat glioma cells. The data was obtained using whole genome technology using NimbleGen microarrays.
Project description:Identification of genes mediating glioma invasion promotes the understanding of glia motility and might result in biologically based therapeutic approaches. To evaluate migration mechanisms operating in vitro versus in vivo, we used C6 rat glioma cells for selecting highly migratory cells in a monolayer migration assay (C6) as well as in brains of nude mice (C6SPGFP), and analyzed in each paradigm the expression profiles of these "fast" cells versus those of the original "slow" cells. Keywords: other
Project description:Identification of genes mediating glioma invasion promotes the understanding of glia motility and might result in biologically based therapeutic approaches. To evaluate migration mechanisms operating in vitro versus in vivo, we used C6 rat glioma cells for selecting highly migratory cells in a monolayer migration assay (C6) as well as in brains of nude mice (C6SPGFP), and analyzed in each paradigm the expression profiles of these fast" cells versus those of the original "slow" cells.
