Mus musculus
Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: E-GEOD-50028E-GEOD-50028
PROVIDER: PRJNA215841 | ENA |
REPOSITORIES: ENA
Publications
The role of retinoic acid in hepatic lipid homeostasis defined by genomic binding and transcriptome profiling.
He Yuqi Y Gong Lei L Fang Yaping Y Zhan Qi Q Liu Hui-Xin HX Lu Yanliu Y Guo Grace L GL Lehman-McKeeman Lois L Fang Jianwen J Wan Yu-Jui Yvonne YJ
BMC genomics 20130828
<h4>Background</h4>The eyes and skin are obvious retinoid target organs. Vitamin A deficiency causes night blindness and retinoids are widely used to treat acne and psoriasis. However, more than 90% of total body retinol is stored in liver stellate cells. In addition, hepatocytes produce the largest amount of retinol binding protein and cellular retinoic acid binding protein to mobilize retinol from the hepatic storage pool and deliver retinol to its receptors, respectively. Furthermore, hepatoc ...[more]
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