Dataset Information


Burkholderia cenocepacia H111

ABSTRACT: The IclR-family regulator BapR controls biofilms formation in B. cenocepacia H111

ORGANISM(S): Burkholderia cenocepacia H111  



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The IclR-family regulator BapR controls biofilm formation in B. cenocepacia H111.

Aguilar Claudio C   Schmid Nadine N   Lardi Martina M   Pessi Gabriella G   Eberl Leo L  

PloS one 20140321 3

In Burkholderia cenocepacia H111, the large surface protein BapA plays a crucial role in the formation of highly structured communities, known as biofilms. We have recently demonstrated that quorum sensing (QS) is necessary for the maximal expression of bapA. In this study we identify BapR, a protein from the IclR family of transcriptional regulators that, in conjunction with QS, controls biofilm formation by affecting the expression of bapA. We present evidence that, in addition to bapA, BapR i  ...[more]

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