Lycalopex culpaeus strain:Andean fox
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA232708 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:gut Metagenome of red fox and corsac fox
| PRJNA646811 | ENA
Project description:Vulpes lagopus breed:blue fox Genome sequencing
| PRJNA644252 | ENA
Project description:The Wnt/β-catenin signaling pathway is a critical regulator of development and stem cell maintenance. Mounting evidence suggests that the context-specific outcome of Wnt signaling is determined by the collaborative action of multiple transcription factors, including members of the highly conserved forkhead box (FOX) protein family. The contribution of FOX transcription factors to Wnt signaling has not been investigated in a systemic manner. Here, by combining β-catenin reporter assays with Wnt pathway-focused qPCR arrays and proximity proteomics of selected FOX family members, we determine that most FOX proteins are involved in the regulation of Wnt pathway activity and the expression of Wnt ligands and target genes. We conclude that FOX proteins are common regulators of the Wnt/β-catenin pathway that may control the outcome of Wnt signaling in a tissue-specific manner.
2023-04-19 | PXD038811 | Pride
Project description:Gray fox (Urocyon cinereoargenteus) and island fox (Urocyon littoralis) Raw sequence reads
| PRJNA478450 | ENA
Project description:Polar Fox Lagoon sediment Metagenome
| PRJNA821074 | ENA
Project description:Comparison of brain gene expression between silver foxes selected for tame behavior and non-selected silver fox.
2005-12-31 | E-MEXP-451 | biostudies-arrayexpress
Project description:Phaseolus vulgaris isolate:Wild Andean Population Pool Genome sequencing
| PRJNA337409 | ENA
Project description:Fecal microbiota of wild and captive Andean bears
| PRJEB21054 | ENA
Project description:Sweat glands play a fundamental role in thermal regulation in man, but the molecular mechanism of their development remains unknown. To initiate analyses, we compared the model of Eda mutant Tabby mice, in which sweat glands were not formed, to wild-type mice. We inferred developmental stages and critical genes based on observations at 7 time points spanning embryonic, postnatal and adult life. In wild-type footpads, sweat gland germs were detected at E17.5. The coiling of secretory portions started at postnatal day 1 (P1), and sweat gland formation was essentially complete by P5. Consistent with a controlled morphological progression, expression profiling revealed stage-specific gene expression changes. Similar to the development of hair follicles the other major skin appendage controlled by EDA sweat gland induction and initial progression was accompanied by Eda-dependent up-regulation of the Shh pathway. During the further development of sweat gland secretory portions, Foxa1 and Foxi1, not at all expressed in hair follicles, were progressively up-regulated in wild-type but not in Tabby footpads. Upon completion of wild-type development, Shh declined to Tabby levels, but Fox family genes remained at elevated levels in mature sweat glands. The results provide a framework for the further analysis of phased downstream regulation of gene action, possibly by a signaling cascade, in response to Eda. This SuperSeries is composed of the following subset Series: GSE14870: Requirement for Shh and Fox family genes at different stages in sweat gland development (E15.5) GSE14871: Requirement for Shh and Fox family genes at different stages in sweat gland development (E16.5) GSE14872: Requirement for Shh and Fox family genes at different stages in sweat gland development (E17.5) GSE14873: Requirement for Shh and Fox family genes at different stages in sweat gland development (P1) GSE14874: Requirement for Shh and Fox family genes at different stages in sweat gland development (P3) GSE14876: Requirement for Shh and Fox family genes at different stages in sweat gland development (P5) GSE14877: Requirement for Shh and Fox family genes at different stages in sweat gland development (Adult) To define target genes of Eda during sweat gland development, we carried out microarray experiments with mouse footpads that from 7 developmental time points including E15.5, E16.5, E17.5, P1, P3, P5 and 8 weeks of wild-type and Tabby mice. Refer to individual Series
2010-05-05 | E-GEOD-14907 | biostudies-arrayexpress
Project description:Consequences of past climate change and recent human persecution on mitogenomic diversity in the arctic fox
| PRJEB34472 | ENA