Genomics

Dataset Information

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Danio rerio


ABSTRACT: Analyzing cold tolerance mechanism in transgenic zebrafish (Danio rerio)

ORGANISM(S): Danio rerio  

PROVIDER: PRJNA254061 | ENA |

REPOSITORIES: ENA

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Analyzing cold tolerance mechanism in transgenic zebrafish (Danio rerio).

Wang Qian Q   Tan Xungang X   Jiao Shuang S   You Feng F   Zhang Pei-Jun PJ  

PloS one 20140724 7


Low temperatures may cause severe growth inhibition and mortality in fish. In order to understand the mechanism of cold tolerance, a transgenic zebrafish Tg (smyd1:m3ck) model was established to study the effect of energy homeostasis during cold stress. The muscle-specific promoter Smyd1 was used to express the carp muscle form III of creatine kinase (M3-CK), which maintained enzymatic activity at a relatively low temperature, in zebrafish skeletal muscle. In situ hybridization showed that M3-CK  ...[more]

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