Genomics

Dataset Information

0

Mus musculus


ABSTRACT: Maternal high-fat diet and obesity compromise fetal hematopoiesis

PROVIDER: PRJNA264852 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
SRR1630380.fastq.gz Fastqsanger.gz
SRR1630381.fastq.gz Fastqsanger.gz
SRR1630382.fastq.gz Fastqsanger.gz
SRR1630373.fastq.gz Fastqsanger.gz
SRR1630383.fastq.gz Fastqsanger.gz
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Publications


<h4>Objective</h4>Recent evidence indicates that the adult hematopoietic system is susceptible to diet-induced lineage skewing. It is not known whether the developing hematopoietic system is subject to metabolic programming via in utero high-fat diet (HFD) exposure, an established mechanism of adult disease in several organ systems. We previously reported substantial losses in offspring liver size with prenatal HFD. As the liver is the main hematopoietic organ in the fetus, we asked whether the  ...[more]

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