Project description:Microarray experiments were performed to reveal the key genes involved in iron homeostasis in the pathogenic yeast Candida glabrata.
Project description:Investigation of centromeres in the pathogenic yeast Candida parapsilosis, shows that the location of two centromeres are polymorphic within this species. The centromeres consist of large inverted repeats (IRs), surrounding unique sequences. New (neo) centromeres have emerged in one C. parapsilosis isolate even though the original CEN location is undamaged. The neocentromeres do not contain IRs, and have no obvious sequence features.
Project description:Candida albicans is an opportunistic pathogenic yeast that is commensally found in variety of host niches. Rhb1 serves as an positive regulator of Tor1 kinase which is the central component of the TOR signaling in controlling several virulence factors. Here, we used microarray to determined changes in transcript profile while the cell lacks the RHB1 gene.
Project description:This work reports the role of the transcription factor Ahr1 in mediating cell size control in the pathogenic yeast Candida albicans. To investigate the role of Ahr1 at Start, we performed a transcriptional profiling by comparing the transcriptome of G1 phase cells of both WT and ahr1 mutant strains.
