Genomics

Dataset Information

2

Homo sapiens


ABSTRACT: Single-cell RNA-seq reveals heterogeneity within human pre-cDCs

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA350790 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
SRR4455090.fastq.gz Fastqsanger.gz
SRR4455100.fastq.gz Fastqsanger.gz
SRR4455110.fastq.gz Fastqsanger.gz
SRR4455120.fastq.gz Fastqsanger.gz
SRR4455130.fastq.gz Fastqsanger.gz
Items per page:
1 - 5 of 1543
altmetric image

Publications

Human dendritic cells (DCs) are derived from distinct circulating precursors that are precommitted to become CD1c+ or CD141+ DCs.

Breton Gaëlle G   Zheng Shiwei S   Valieris Renan R   Tojal da Silva Israel I   Satija Rahul R   Nussenzweig Michel C MC  

The Journal of experimental medicine 20161118 13


In humans, conventional dendritic cells (cDCs) exist as two unique populations characterized by expression of CD1c and CD141. cDCs arise from increasingly restricted but well-defined bone marrow progenitors that include the common DC progenitor that differentiates into the pre-cDC, which is the direct precursor of cDCs. In this study, we show that pre-cDCs in humans are heterogeneous, consisting of two distinct populations of precursors that are precommitted to become either CD1c<sup>+</sup> or  ...[more]

Similar Datasets

2019-01-01 | S-EPMC6599345 | BioStudies
| GSE89232 | GEO
2017-01-01 | S-EPMC5775029 | BioStudies
2019-01-01 | S-EPMC6368609 | BioStudies
2020-01-01 | S-EPMC7145626 | BioStudies
2019-01-01 | S-EPMC6637240 | BioStudies
2015-01-01 | S-EPMC4447135 | BioStudies
2019-01-01 | S-EPMC6609986 | BioStudies
2020-01-01 | S-EPMC7314468 | BioStudies
2015-01-01 | S-EPMC4482058 | BioStudies