Genomics

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ZBTB18 is a repressor of mesenchymal genes in Glioblastoma


ABSTRACT: ZBTB18 is a repressor of mesenchymal genes in Glioblastoma

PROVIDER: PRJNA381482 | ENA |

REPOSITORIES: ENA

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Glioblastoma (GBM) comprises distinct subtypes characterized by their molecular profile. Mesenchymal identity in GBM has been associated with a comparatively unfavorable prognosis, primarily due to inherent resistance of these tumors to current therapies. The identification of molecular determinants of mesenchymal transformation could potentially allow for the discovery of new therapeutic targets. Zinc Finger and BTB Domain Containing 18 (ZBTB18/ZNF238/RP58) is a zinc finger transcriptional repr  ...[more]

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