Homo sapiens
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA393929 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Brain metastatic disease occurs in 10-30% of metastatic breast cancer cases. The incidence of brain metastases is increasing with median overall survival < 2 years for patients. In order to better characterize oncogenic pathway activity pertinent to breast cancer brain metastasis, exome capture RNA sequencing was carried out on patient matched primary breast with brain metastatic tumor samples for 45 cases of breast cancer brain metastasis (N= 90 samples). Here, exome capture RNA sequencing data is deposited as sequencing batch corrected log2 transformed trimmed M of means (TMM) normalized counts per million (CPM) (log2(TMM-CPM +1) gene expression values (n=16,714 protein coding genes; N=90 tumor samples).
2021-11-12 | GSE184869 | GEO
Project description:Brain metastatic disease occurs in 10-30% of metastatic breast cancer cases. The incidence of brain metastases is increasing with median overall survival < 2 years for patients. In order to better characterize oncogenic pathway activity pertinent to breast cancer brain metastasis, exome capture RNA sequencing was carried out on patient matched primary breast with brain metastatic tumor samples for 45 cases of breast cancer brain metastasis (N= 90 samples). Here, exome capture RNA sequencing data is deposited as sequencing batch corrected log2 transformed trimmed M of means (TMM) normalized counts per million (CPM) (log2(TMM-CPM +1) gene expression values (n=16,714 protein coding genes; N=90 tumor samples).
2022-04-01 | GSE173661 | GEO
Project description:Expression profiling in breast cancer brain metastases compared to breast cancers and primary brain tumors
| PRJNA392050 | ENA
Project description:Identification of novel metastases-suppressor genes involved in breast cancer brain metastases (BCBM) formation
| PRJNA190627 | ENA
Project description:A BRCA1 Deficient-Like Signature is Enriched in Breast Cancer Brain Metastases
| PRJNA187530 | ENA
Project description:Genome-wide DNA methylation profiling of brain metastases from lung cancer, breast cancer, and melanoma samples. The Illumina Infinium 450K Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 450,000 methylation sites in formalin-fixed paraffin-embedded (FFPE) samples from brain metastases. Samples included 30 breast cancer brain metastases, 18 lung cancer brain metastases, 37 melanoma brain metastases, and 4 samples with brain metastases from patients with uncertain primary.
2018-08-28 | GSE108576 | GEO
Project description:A 13-gene signature predicting rapid development of brain metastases in breast cancer
| PRJNA167135 | ENA
Project description:Transcriptome analysis of patient-derived xenograft models of HER2+ breast cancer brain metastases
| PRJNA319811 | ENA