Genomics

Dataset Information

0

Mus musculus


ABSTRACT: Genome-wide analysis between murine invariant NKT cells and CD4+ T cells

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA400470 | ENA |

REPOSITORIES: ENA

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Publications

Comparison of Invariant NKT Cells with Conventional T Cells by Using Gene Set Enrichment Analysis (GSEA).

Oh Sae Jin SJ   Ahn Ji Ye JY   Chung Doo Hyun DH  

Immune network 20111231 6


BACKGROUND: Invariant Natural killer T (iNKT) cells, a distinct subset of CD1d-restricted T cells with invariant Vαβ TCR, functionally bridge innate and adaptive immunity. While iNKT cells share features with conventional T cells in some functional aspects, they simultaneously produce large amount of Th1 and Th2 cytokines upon T-cell receptor (TCR) ligation. However, gene expression pattern in two types of cells has not been well characterized. METHODS: we performed comparative microarray analys  ...[more]

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