Bidirectional Introgression between Mus musculus domesticus and Mus spretus.

ABSTRACT: Introgressed variants from other species can be an important source of genetic variation because they may arise rapidly, can include multiple mutations on a single haplotype, and have often been pretested by selection in the species of origin. Although introgressed alleles are generally deleterious, several studies have reported introgression as the source of adaptive alleles-including the rodenticide-resistant variant of Vkorc1 that introgressed from Mus spretus into European populations of Mus musculus domesticus. Here, we conducted bidirectional genome scans to characterize introgressed regions into one wild population of M. spretus from Spain and three wild populations of M. m. domesticus from France, Germany, and Iran. Despite the fact that these species show considerable intrinsic po

SUBMITTER: Banker SE 

PROVIDER: S-EPMC8784167 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature