Project description:We sequenced RNA from adult mouse spinal cord and from cell sorted Nova2-cKO neurons (crossed with Emx1-Cre, Gad2-Cre, Pcp2-Cre driver mice) and from Nova2.Ptbp2-dKO to compare gene expression level, and alternative splicing events.
Project description:To understand the mechanisms through which JunB regulates Tregs-mediated immune regulation, we examined the global gene expression profiles in the JunB WT and KO Tregs by performing RNA sequencing (RNA-seq) analysis.
Project description:Histones were isolated from brown adipose tissue and liver from mice housed at 28, 22, or 8 C. Quantitative top- or middle-down approaches were used to quantitate histone H4 and H3.2 proteoforms. See published article for complimentary RNA-seq and RRBS datasets.
Project description:ATAC-seq profiling of Nfat5 KO and wild type macrophages derived from bone marrow (primary cells), treated or not with Lipopolysaccharide (LPS).