Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptional profiling of mouse plasma cells (population RNA-Seq)

ABSTRACT: Transcriptional profiling of mouse plasma cells (population RNA-Seq)

PROVIDER: PRJNA476324 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Transcriptional profiling of mouse plasma cells

Project description:Transcriptional profiling of mouse plasma cells

| PRJNA476321 | ENA

Transcriptional profiling of mouse plasma cells (scRNA-Seq)

Project description:Transcriptional profiling of mouse plasma cells (scRNA-Seq)

| PRJNA476323 | ENA

Transcriptional profiling of mouse plasma cells (population RNA-Seq)

Project description:CD138-high plasma cell subsets were analyzed by RNA-sequencing to identify gene expression differences between long- and short-lived plasma cells. Five different CD138-high subsets were analyzed based upon differential B220 expression and uptake of the fluorescent glucose analog 2NBDG: splenic B220+2NBDG-, B220+2NBDG+, B220-2NBDG-, B220-2NBDG+, and bone marrow B220-2NBDG+ cells.

2018-07-18 | GSE115858 | GEO

Plasma DNA end analysis (mouse)

Project description:Plasma DNA end analysis (mouse)

| EGAS00001006700 | EGA

Jagged ends of plasma DNA (mouse)

Project description:Jagged ends of plasma DNA (mouse)

| EGAS00001005563 | EGA

Transcriptional profiling of mouse plasma cells (scRNA-Seq)

Project description:CD138-high plasma cell subsets were analyzed by single cell RNA-sequencing to identify gene expression differences between long- and short-lived plasma cells. Five different CD138-high subsets were analyzed based upon differential B220 expression and uptake of the fluorescent glucose analog 2NBDG: splenic B220+2NBDG-, B220+2NBDG+, B220-2NBDG-, B220-2NBDG+, and bone marrow B220-2NBDG+ cells.

2018-07-18 | GSE115859 | GEO

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells

Project description:Upon encounter with antigen, mature B cells undergo complex changes in their physiological state and anatomical localization, and initiate a differentiation process that ultimately produces antibody-secreting cells (ASCs), a major effector population of the immune system. To better characterize this process we have defined the transcriptome of all stages of B cell terminal differentiation by performing a large scale RNA-seq experiment. This analysis provides a molecular signature of ASC populations that highlights the stark transcriptional divide between B cells and plasma cells, and also enables the demarcation ASCs based on location, cell cycle status and maturity. The gene expression changes strongly correlated with cell division history and the acquisition of permissive histone modifications and were clearly evident in the small subset of regulatory genes containing super-enhancers. These findings highlight the core transcriptional program that guides B cell terminal differentiation and the production of antibody, essential processes in the immune response. Transcriptional profiling of ex vivo and in vitro B cell and plasma cell populations in mice using RNA sequencing

2015-04-01 | E-GEOD-60927 | biostudies-arrayexpress

Plasma DNA profile in DNASE1L3 deficiency-Mouse AAV samples

Project description:Plasma DNA profile in DNASE1L3 deficiency-Mouse AAV

| EGAS00001004409 | EGA

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells

2015-04-01 | GSE60927 | GEO

Transcriptional Profiling of NASH mouse models

Project description:Transcriptional Profiling of NASH mouse models

| PRJNA683606 | ENA