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A Human Liver Cell Atlas reveals Heterogeneity and Epithelial Progenitors

ABSTRACT: A Human Liver Cell Atlas reveals Heterogeneity and Epithelial Progenitors

PROVIDER: PRJNA511895 | ENA |

REPOSITORIES: ENA

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A human liver cell atlas reveals heterogeneity and epithelial progenitors.

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A Human Liver Cell Atlas reveals Heterogeneity and Epithelial Progenitors

Project description:We perfomed single-cell RNA-sequnecing of around 10,000 cells from normal human liver tissue to construct a human liver cell atlas. We reveal previously unknown subtypes in different cell type compartments. We also use our normal liver cell atlas to infer perturbed phenoytpes of cells from HCC samples, human cells engrafted into a mouse liver and liver organoids.

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