Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-Seq of CircHomer1a shRNA Knockdown vs. scrambled shRNA Control Mouse Orbital Frontal Cortex

ABSTRACT: RNA-Seq of CircHomer1a shRNA Knockdown vs. scrambled shRNA Control Mouse Orbital Frontal Cortex

PROVIDER: PRJNA559856 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

RNA-Seq of CircHomer1a shRNA Knockdown vs. scrambled shRNA Control Mouse Orbital Frontal Cortex

Project description:We report the application of RNA-sequencing to profile gene expression changes associated with shRN- mediated knockdown of circHomer1a RNA in mouse orbital frontal cortex

2020-01-01 | GSE135721 | GEO

RNA sequencing in 12-week old orbital frontal cortex in circHomer1/Homer1b knockdown and control mice

Project description:These are RNA sequencing data from 12 week old orbital frontal cortex from mice who received a shRNA targeting circHomer1 and Homer1b (double knockdown) or control shRNA (scramble)

2022-01-01 | GSE160874 | GEO

Effect of Juvenile Environmental Tobacco Smoke Exposure on the Rat Frontal Cortex Neuroproteome

Project description:Exposure to secondhand tobacco smoke during early childhood has been linked with an increased risk for behavioral disorders, yet little is known regarding how brain development is impacted. Using an environmental tobacco smoke (ETS) passive inhalation model, this study assesses the neurodevelopmental impact of juvenile exposure during a critical period of frontal cortex development, specifically that of the rat orbital neocortex between postnatal days 8 and 22. Agnostic shotgun proteomics was employed to discern the biomolecular shift within this rapidly developing brain region that is responsible for higher-order behavioral control. The orbital cortex neuroproteome was assessed between ETS-exposed and room-air control animals employing a label-free shotgun approach with data-independent acquisition. Following protein roll-up, a total of X protein were found statistically altered in quantity out of Y total proteins identified. These results implicate a prominent shift within metabolic processes and synaptic organization related to excitatory and inhibitory neurotransmission. Findings derived from this dataset may further our understanding of how secondhand smoke exposure can perturb the orbital frontal cortex and result in developmental behavioral disorders.

2018-12-17 | PXD011744 | Pride

Effect of Juvenile Environmental Tobacco Smoke Exposure on the Rat Frontal Cortex Neuroproteome

2020-05-26 | PXD007690 | Pride

RNA sequencing in 12-week old orbital frontal cortex in circHomer1/Homer1b knockdown and control mice

Project description:RNA sequencing in 12-week old orbital frontal cortex in circHomer1/Homer1b knockdown and control mice

| PRJNA674708 | ENA

shRNA profiling of human myeloma cell line jjn3 with non-specific, scrambled shrna or cks1b shrna

Project description:This series represents Affymetrix U133Plus2.0 data sets of JJN3 transduced with levivirus expressing non-specific scrambled shRNA or CKS1B shRNA Experiment Overall Design: This series represents Affymetrix U133Plus2.0 data sets of JJN3 transduced with levivirus expressing non-specific scrambled shRNA or CKS1B shRNA

2008-06-12 | E-GEOD-3369 | biostudies-arrayexpress

Parkinson Disease Frontal Cortex ncRNA Profiling

Project description:Parkinson Disease Frontal Cortex ncRNA Profiling

| PRJNA659521 | ENA

Affymetrix U133Plus2.0 data sets of Human Myeloma Cellline JJN3 with non-specific, scrambled shRNA or CKS1B shRNA

Project description:This series represents Affymetrix U133Plus2.0 data sets of JJN3 transduced with levivirus expressing non-specific scrambled shRNA or CKS1B shRNA Keywords: JJN3 CKS1B shRNA

2006-03-31 | GSE3369 | GEO

Transcriptome Alterations in Myotonic Dystrophy Frontal Cortex

Project description:Transcriptome Alterations in Myotonic Dystrophy Frontal Cortex

| PRJNA661286 | ENA

Microarrays of frontal cortex (area 8) of Parkinson cases and controls

Project description:Microarrays of frontal cortex (area 8) of Parkinson cases and controls

2013-06-02 | E-MTAB-1194 | biostudies-arrayexpress