Project description:Small RNA-Seq analysis of on stool samples from an Italian cohort of 120 healthy individuals with three dietary habits. The cohort includes 72 women and 48 men included an equal proportion of vegetarians, vegans and omnivores.
Project description:Small RNA-Seq analysis of circulating small RNAs performed on plasma samples from an Italian cohort of 120 healthy individuals with three dietary habits. The cohort includes 72 women and 48 men included an equal proportion of vegetarians, vegans and omnivores.
Project description:Illumina Infinium EPIC HumanMethylation BeadChip data from saliva DNA samples from a healthy elderly cohort with individuals in the age range 70-95 in Southwest Sweden. The cohort was stratified into study groups based on participants´answers to a questionnaire of different lifestyle factors including vitamin supplementations, smoking and drinking habits, physical activity (per year), sun exposure and eating habits. Vitamin D intake was evaluated from the vitamin D supplementation (alone or in a multivitamin complex), dietary vitamin D intake (fish and seafood frequency) and vitamin D synthesis in the skin (sunlight exposure and use of sunscreen). Differential methylation analysis was performed for all the study groups and the combination of different factors with vitamin D supplementation. Gender, age, smoking and alcohol (SD and frequency) were used as covariates in the analyses. Only the study groups referred to the conclusions of the study are shown.
Project description:The impressive increase of performance and versatility of the MS-instrumentation, which today represents an indispensable tool in proteomics, has determined a considerable growth of the so-called paleoproteomics as interdisciplinary approach, which involve chemists, archaeologists, and evolutionary biologists. Archaeological proteins residues can inform us about production, use, state and preservation of a material, about evolutionary and ecological divergences, dietary habits and past cultures. This paper reports the results of the characterization of proteins extracted from the pottery of the Maltese site of Baħrija, the guide-site for the local Iron Age (11th-8th century BCE). Proteomic data here reported confirm that one the major issue of these kind of studies is represented by contamination of animal and human agents that may complicate endogenous protein identification and authentication. In this context, the lack of archaeozoological and paleobotanical data for the settlement at Baħrija makes the outcomes of the proteomic analysis even more relevant in terms of contributing to reconstruction foodways and dietary habits of that ancient community. Particularly, our data revealed that wheat turned out to be a cereal used in the diet of the ancient community of Bahrija.