Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

H3K27me3 and H3K4me3 ChIP-seq on DMSO or MAK683 treated cancer cell

ABSTRACT: H3K27me3 and H3K4me3 ChIP-seq on DMSO or MAK683 treated cancer cell

PROVIDER: PRJNA761398 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

H3K27me3 and H3K4me3 ChIP-seq on DMSO and EPZ6438 treated CD34+ HSPCs

Project description:H3K27me3 and H3K4me3 ChIP-seq on DMSO and EPZ6438 treated CD34+ HSPCs

| PRJNA602858 | ENA

ChIP-Seq H3K4me3 in Jurkat treated with either OICR-9429, PBIT or DMSO

Project description:To assess whether BH4Ds are more or less sensitive than sharp H3K4me3 peaks to perturbation of H3K4me3 levels, we performed H3K4me3 ChIP-seq experiments from Jurkat cells treated with DMSO or with either 2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one (PBIT), a specific inhibitor of JARID1 family of H3K4me3 demethylases, also known as KDM5, or OICR-9429, an inhibitor of the MLL-WDR5, previously shown to decrease cellular levels of H3K4me3.

2021-04-16 | GSE164184 | GEO

ChIP-Seq H3K4me3 in Jurkat treated with either OICR-9429, PBIT or DMSO

Project description:ChIP-Seq H3K4me3 in Jurkat treated with either OICR-9429, PBIT or DMSO

| PRJNA689441 | ENA

ChIP-on-chip from multiple donors of BM-MSCs with H3K4me3 and H3K27me3

Project description:Bone marrow-derived multipotent stromal cells (BM-MSCs) exhibit therapuetically valuable properties, including the capacity to differentiate into skeletal tissues and modulate immune system activity. These properties depend on proper regulation of dynamic gene expression in response to environmental and developmental stimuli. This study used chromatin immunoprecipitation (ChIP) coupled with human promoter tiling microarray analysis (ChIP-on-chip) to profile histones H3K4me3 and H3K27me3 at promoters genome-wide. The goal of the study was to identify gene promoters marked by H3K27me3 and H3K4me3 in BM-MSCs. ChIP-on-chip performed with antibodies to H3K4me3 and H3K27me3 on BM-MSCs from 3 different donors (labeled 1632, 167696, and 8F3560) and with technical replicates.

2015-02-09 | E-GEOD-64172 | biostudies-arrayexpress

ChIP-seq for H3K4me3, H3K27me3, H3K79me2 in MCF10A cells

Project description:ChIP-seq for H3K4me3, H3K27me3, H3K79me2 in MCF10A cells

| PRJNA431792 | ENA

ChIP-seq for H3K4me3, H3K27me3, H3K79me2 in MCF10A cells

Project description:We performed ChIP-Seq against histones H3K4me3, H3K27me3, and H3K79me2 in MCF10A cells to identify transcription factors with bivalent and pseudo-bivalent epigenetic modifications.

2018-02-01 | GSE109721 | GEO

ChIP-on-chip from multiple donors of BM-MSCs with H3K4me3 and H3K27me3

2015-02-09 | GSE64172 | GEO

Genome-wide H3K4me3 after MK2206/DMSO treatment of T47D cells

Project description:We perfomed ChIP-seq using H3K4me3 antibodies in T47D cells after 24 hour treatment with the AKT inhibitor MK2206 or DMSO. We demonstrate that at a selected group of loci H3K4me3 is affected by AKT inhibition.

2016-06-14 | GSE80592 | GEO

ChIP-seq analyses of H3K27me3 and H3K4me3 in JMJD3c-hESCs

Project description:We generated the human ES lines, in which the genome-wide reduction of H3K27me3 can be induced by the ectopic expression of catalytic domain of histone demethylase JMJD3 with doxycycline treatment (JMJD3c-hESCs). Genome-wide changes in H3K27me3 and H3K4me3 after JMJD3c overexpression were examined by ChIP-seq analyses.

2016-10-18 | GSE80086 | GEO

ChIP-seq-based analysis of differential K27me3 coverage in neuroblastoma cell lines treated with epigenetic drugs

Project description:The impact of drugs inhibiting DNA methylation (5-aza-2'-deoxycytodine, DAC) and EZH2 (EPZ-6438) on H3K27me3 coverage was analyzed in two neuroblastoma cell lines. Parallel analyses investigated associated changes in RNA expression and DNA methylation. The neuroblastoma cell lines Be(2)-C and IMR5-75 were treated with a combination of DAC and EPZ-6438. Controls were treated with solvent (DMSO). H3K27me3 ChIP seq was done to investigate treatment-related changes of this mark. In addition, H3K4me3 and H3K27ac ChIP seq was done in DMSO treated samples to identify putative regulatory regions.

2016-09-08 | E-GEOD-80445 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data