SARS-CoV2 Immunocomplex by LC-MS/MS on vaccinated cohort

ABSTRACT: We describe the development of a highly specific, mulitplexed targeted proteomic LC-MS/MS assay for accurate quantitation of immunoprotective-proteins (including several classes of antibodies and complement) to SARS CoV2 S1 spike protein. We demonstrate how antibodies/complement levels can be monitored in response to vaccination with or without previous infection and show their altered level of protection against variants of concern.

ORGANISM(S): Homo Sapiens

SUBMITTER: Wendy Heywood  

PROVIDER: PXD028450 | panorama | Thu Jul 14 00:00:00 BST 2022

REPOSITORIES: PanoramaPublic