Proteomics

Dataset Information

0

E.coli - Whole organism, Yfp fusion library, YFP normalized data (Taniguchi,science,2010)


ABSTRACT: abundance based on YFP normalized data, YFP fusion library, Interaction consistency score: 6.5, Coverage: 24

ORGANISM(S): 511145

SUBMITTER: Christian von Mering  

PROVIDER: 3472819899 | PAXDB | 2010

REPOSITORIES: PAXDB

Dataset's files

Source:
Action DRS
bioprojects-abundance-files-v4.0.zip Other
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Publications

Quantifying E. coli proteome and transcriptome with single-molecule sensitivity in single cells.

Taniguchi Yuichi Y   Choi Paul J PJ   Li Gene-Wei GW   Chen Huiyi H   Babu Mohan M   Hearn Jeremy J   Emili Andrew A   Xie X Sunney XS  

Science (New York, N.Y.) 20100701 5991


Protein and messenger RNA (mRNA) copy numbers vary from cell to cell in isogenic bacterial populations. However, these molecules often exist in low copy numbers and are difficult to detect in single cells. We carried out quantitative system-wide analyses of protein and mRNA expression in individual cells with single-molecule sensitivity using a newly constructed yellow fluorescent protein fusion library for Escherichia coli. We found that almost all protein number distributions can be described  ...[more]

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