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Hs_C-HPP_DentalPulpTails_N-terminomics

ABSTRACT: Hs_C-HPP, dental pulp proteome, TAILS technique

REANALYSIS of: PXD002264

INSTRUMENT(S): 6520 Triple Quadrupole LC/MS

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Others

SUBMITTER: Eckhard U, Marino G, Abbey SR, Tharmarajah G, Matthew I, Overall CM

PROVIDER: PAe005343 | PeptideAtlas | 2015-12-31

REPOSITORIES: PeptideAtlas

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The Human Dental Pulp Proteome and N-Terminome: Levering the Unexplored Potential of Semitryptic Peptides Enriched by TAILS to Identify Missing Proteins in the Human Proteome Project in Underexplored Tissues.

Eckhard Ulrich U Marino Giada G Abbey Simon R SR Tharmarajah Grace G Matthew Ian I Overall Christopher M CM

Journal of proteome research 20150814 9

An underexplored yet widespread feature of the human proteome is the proteolytic proteoforms of proteins. We used terminal amine isotopic labeling of substrates (TAILS), a high-content N-terminal positional proteomics technique, for in-depth characterization of the human dental pulp proteome from its N-terminome and to provide data for the Chromosome-centric Human Proteome Project (C-HPP). Dental pulp is a unique connective tissue maintaining tooth sensation and structure by supporting a single ...[more]

PMID: 26258467

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