Dataset Information
NatB - N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap, instrument model
ORGANISM(S): Homo Sapiens (human) Saccharomyces Cerevisiae (baker's Yeast)
SUBMITTER: 
Petra Van Damme
PROVIDER: PRD000376 | Pride | 2012-07-20
REPOSITORIES: Pride
Publications
N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
Proceedings of the National Academy of Sciences of the United States of America 20120718 31
Protein N-terminal acetylation (Nt-acetylation) is an important mediator of protein function, stability, sorting, and localization. Although the responsible enzymes are thought to be fairly well characterized, the lack of identified in vivo substrates, the occurrence of Nt-acetylation substrates displaying yet uncharacterized N-terminal acetyltransferase (NAT) specificities, and emerging evidence of posttranslational Nt-acetylation, necessitate the use of genetic models and quantitative proteomi ...[more]
