Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap, LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Hannes Hahne
PROVIDER: PXD000061 | Pride | 2013-01-10
REPOSITORIES: Pride
Hahne Hannes H Sobotzki Nadine N Nyberg Tamara T Helm Dominic D Borodkin Vladimir S VS van Aalten Daan M F DM Agnew Brian B Kuster Bernhard B
Journal of proteome research 20130118 2
The post-translational modification of proteins with N-acetylglucosamine (O-GlcNAc) is involved in the regulation of a wide variety of cellular processes and associated with a number of chronic diseases. Despite its emerging biological significance, the systematic identification of O-GlcNAc proteins is still challenging. In the present study, we demonstrate a significantly improved O-GlcNAc protein enrichment procedure, which exploits metabolic labeling of cells by azide-modified GlcNAc and copp ...[more]