Ontology highlight
ABSTRACT:
INSTRUMENT(S): QSTAR
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture, Keratinocyte
SUBMITTER: Tuula Nyman
LAB HEAD: Tuula A Nyman
PROVIDER: PXD000677 | Pride | 2014-08-05
REPOSITORIES: Pride
Molecular & cellular proteomics : MCP 20140705 10
Viral double-stranded RNA (dsRNA) is the most important viral structure recognized by cytosolic pattern-recognition receptors of the innate immune system, and its recognition results in the activation of signaling cascades that stimulate the production of antiviral cytokines and apoptosis of infected cells. 14-3-3 proteins are ubiquitously expressed regulatory molecules that participate in a variety of cellular processes, and 14-3-3 protein-mediated signaling pathways are activated by cytoplasmi ...[more]