Ontology highlight
ABSTRACT:
INSTRUMENT(S): ion trap
ORGANISM(S): Borrelia Burgdorferi 297
TISSUE(S): Skin
SUBMITTER: Schnell Gilles
LAB HEAD: Laurence Sabatier
PROVIDER: PXD000879 | Pride | 2016-07-09
REPOSITORIES: Pride
Schnell Gilles G Boeuf Amandine A Westermann Benoît B Jaulhac Benoît B Lipsker Dan D Carapito Christine C Boulanger Nathalie N Ehret-Sabatier Laurence L
Molecular & cellular proteomics : MCP 20150224 5
Lyme disease is the most important vector-borne disease in the Northern hemisphere and represents a major public health challenge with insufficient means of reliable diagnosis. Skin is rarely investigated in proteomics but constitutes in the case of Lyme disease the key interface where the pathogens can enter, persist, and multiply. Therefore, we investigated proteomics on skin samples to detect Borrelia proteins directly in cutaneous biopsies in a robust and specific way. We first set up a disc ...[more]