Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): B Cell
DISEASE(S): Multiple Myeloma
SUBMITTER: Natalia Kunowska
LAB HEAD: Niall Dillon
PROVIDER: PXD001273 | Pride | 2016-05-04
REPOSITORIES: Pride
Nucleic acids research 20150120 3
The large number of chemical modifications that are found on the histone proteins of eukaryotic cells form multiple complex combinations, which can act as recognition signals for reader proteins. We have used peptide capture in conjunction with super-SILAC quantification to carry out an unbiased high-throughput analysis of the composition of protein complexes that bind to histone H3K9/S10 and H3K27/S28 methyl-phospho modifications. The accurate quantification allowed us to perform Weighted corre ...[more]