Ontology highlight
ABSTRACT:
INSTRUMENT(S): Synapt MS
ORGANISM(S): Cupriavidus Metallidurans
TISSUE(S): Prokaryotic Cell
SUBMITTER: Sacha Baginsky
LAB HEAD: Baginsky, Sacha
PROVIDER: PXD001356 | Pride | 2016-05-04
REPOSITORIES: Pride
Herzberg Martin M Dobritzsch Dirk D Helm Stefan S Baginsky Sacha S Nies Dietrich H DH
Metallomics : integrated biometal science 20141101 11
Zinc is a central player in the metalloproteomes of prokaryotes and eukaryotes. We used a bottom-up quantitative proteomic approach to reveal the repository of the zinc pools in the proteobacterium Cupriavidus metallidurans. About 60% of the theoretical proteome of C. metallidurans was identified, quantified, and the defect in zinc allocation was compared between a ΔzupT mutant and its parent strain. In both strains, the number of zinc-binding proteins and their binding sites exceeded that of th ...[more]